Regis Bassin

Knee osteoarthritis: Intra-Articular Injections of Platelet-Rich Plasma, Adipose Mesenchymal Stem Cells, and Bone Marrow Mesenchymal Stem Cells Associated with Better Outcomes Than Hyaluronic Acid and Saline  The purpose of this work was to perform a network meta-analysis to evaluate clinical efficacy and treatment-related adverse events (AEs) of intra-articular hyaluronic acid (HA), leukocyte-poor platelet-rich plasma (LP-PRP), leukocyte-rich… Continue reading Meta-analysis: Rheumatology

Stretch marks: In vitro study and assessment of combined treatment with PRP and sodium ascorbate on fibroblasts

What is important to note for the preparation of Platelet-Rich Plasma (PRP) with respect to the new* MDR (Medical Device Regulation) 2017/745

Platelet-Rich Plasma Versus Hyaluronic Acid in the Treatment of Knee Osteoarthritis: A Meta-analysis of 26 Randomized Controlled Trials  The purpose of this work was to compare the effectiveness and safety of platelet-rich plasma (PRP) and hyaluronic acid (HA) in patients with adult knee osteoarthritis (KOA) using Cochrane methodology.  Only randomized controlled trials (RCTs) with an experimental… Continue reading Meta-analysis: Osteoarthritis

PRP alone or combined with HA are growth factors reservoirs that promote angiogenesis in in-vitro cell tissue-engineering applications  In this in vitro study, the authors evaluated and compared the ability of three platelet-derived preparations: platelet-rich-plasma (PRP, prepared with CuteCell® medical device), PRP-hyaluronic acid (PRP-HA, Cellular Matrix®) and platelet lysates (PL) at various concentrations (5 – 40%)… Continue reading Study: Basic research

First study to report A-PRP treatment effect for SUI in Female Stress Urinary Incontinence (SUI)  The authors evaluated the efficacy of a local injection of autologous platelet-rich plasma (A-PRP) as a treatment for women with stress urinary incontinence in a prospective pilot study involving 20 patients.  PRP was injected into the anterior vaginal mucosa around the… Continue reading Study: Urology

Regen A-PRP in patients with partial-thickness rotator cuff tears or tendinopathy leads to significantly improved short-term pain relief and function compared with corticosteroid (CS) injection  The authors perform a randomized controlled trial comparing A-PRP with standard CS injection in providing pain relief and improved function in patients with rotator cuff tendinopathy and partial thickness rotator… Continue reading Study: Tendinopathy