Regis Bassin

Efficacy and safety of the combination of PRP + non-crosslinked hyaluronic acid versus hyaluronic acid, in mono-injection, in symptomatic knee osteoarthritis, randomized controlled phase III trial, single blind. The purpose of this randomized, controlled, multicenter, non-inferiority clinical trial was to compare the efficacy and safety of the combination of PRP and non-crosslinked hyaluronic acid (Cellular… Continue reading Randomized clinical trial (RCT), Knee osteoarthritis

PRP – Rational/Indication Does current clinical evidence support the use of PRP for knee OA For which degrees of knee OA is PRP best indicated? Can PRP be used in severe knee OA (KL4)? Is PRP indicated for the treatment of Patellofemoral OA (PFOA)? Are there specific contraindications for the use of PRP for knee… Continue reading ORthoBIologics InitiaTive (ORBIT) Consensus from ESSKA – Section 1

Platelet-Rich Plasma in Female Androgenetic Alopecia: A Comprehensive Systematic Review and Meta-Analysis In this work, Zhou et al.3 summarize different treatment regimes in female androgenetic alopecia (AGA), and quantitively analyze the efficacy of PRP in this disease. They evaluated 636 studies and 12 trials from six databases (MEDLINE, EMBASE, Web of Science, Cochrane Central Register of Controlled… Continue reading Study: Female Androgenetic Alopecia

Platelet-Rich Plasma in The new Medical Devices Regulation (2017/745/EU), applicable since May 2021 in EU, will replace the existing Medical Devices Directives (93/42/EEC). This regulation provides a framework for the manufacture, modification, and use of devices when equivalent devices are not commercially available (Article 5 of the Medical Device Regulation). In these situations, health care… Continue reading New Medical Device Regulation

Platelet concentration is the number of platelets per unit of volume. Usually, platelet concentration is expressed in millions per ml. The platelet concentration factor is the ratio between platelet concentration in PRP and baseline platelet concentration in whole blood and is generally expressed as nX, where n is the value of ratio. When all platelets… Continue reading Platelet concentration & concentration factor

Autologous regenerative stimulants for bone allograft implantation In their report, Vorobyov et al. present a clinical case where a combination of allogeneic osteoplastic materials with autologous platelet-rich plasma is used to reconstruct a cavity defect in the tibia. Firstly, the authors describe the basic principles of orthobiology and the different surgical techniques for bone reconstruction using bone… Continue reading Study: Orthopedic surgery

Synergistic Effects of Autologous Platelet-Rich Plasma (a-PRP) and Hyaluronic Acid (HA) Injections on Facial Skin Rejuvenation The demand for facial skin rejuvenation is increasing. Facial skin aging is clinically associated with a number of features like changes in elasticity and reduced hydration. In a pilot study (J Am Acad Dermatol. 2017),  Hersant et al. reported preliminary results… Continue reading Study : Facial Skin Rejuvenation

European Standard EN 16844:2017+A2 (August 2019) The European Standard EN 16844:2017+A2 defines the set of requirements deemed essential for the delivery of aesthetic medicine services (non-surgical medical treatments). This European Standard was adopted by the European Committee for Standardization (CEN) on December 20, 2017 and includes Amendment 2 adopted by CEN on April 16, 2019.… Continue reading Regulatory update : European Standard