NEW COLLAGEN
Histologic evidence of new collagen formulation using platelet rich plasma in skin rejuvenation.
In this prospective controlled clinical study, the authors evaluated the efficacy of an intradermal injection of RegenPRP for human facial rejuvenation (20 patients) by performing histological examinations before and after treatment and measuring the mean optical densities (MODs) of collagen.
• The authors observed that the MOD of collagen fibers was clearly higher on the PRP-treated side compared to the saline injected side (p < 0.001). These data are in line with previous in vivo work showing the effect of RegenPRP on the rejuvenation of photoaged skin in nude mice4.
• The authors observed no serious side effects following RegenPRP treatment.
Figure1: Graph illustrating the the mean optical density for collagen measured at pre-treatment, saline- or PRP-treated condition. p<0.001 compared to pre-treatment and saline condition
REFERENCE
3 Abuaf, O.K., et al., Histologic Evidence of New Collagen Formulation Using Platelet Rich Plasma in Skin Rejuvenation: A Prospective Controlled Clinical Study. Ann Dermatol, 2016. 28(6): p. 718-724.
4 Cho, J.M., et al., Effect of platelet-rich plasma on ultraviolet b-induced skin wrinkles in nude mice. J Plast Reconstr Aesthet Surg, 2011. 64(2):